Top 7 AI Amazon PPC Tools That Actually Make You More Profit (2025 Update)

We tested 10+ AI Powered Amazon Ads tools so you don’t have to.

AI Is Changing Amazon PPC, But Most Tools Aren’t Keeping Up

Everyone claims “AI” is transforming Amazon advertising, but most tools only tweak bids and call it intelligence.

At Astra by Sellrbox, we manage millions in ad spend for brands and agencies and see firsthand which platforms actually deliver AI-driven results.

After testing 10 of the most popular systems, here are the 7 AI Amazon PPC tools that genuinely make you more profit in 2025, ranked by capability, usability, and ROI.

AI Amazon Ads Software Comparison

Software	Pricing	Free Trial	Customer Support	Best For
Astra by Sellrbox	Starting price is $119 + % of Ad Revenue *Performance Based	Yes — 30 days	High-touch support: strategy calls, audits, Amazon expert team.	Brands wanting full-workflow automation (research → campaigns → bids → negatives) with optional manual overrides and adaptive learning using Machine Learning.
Perpetua	Starting price is ~$695/month + % of Ad Spend *Ad Spend Based	Demo only	Email & chat; dedicated Customer Success Manager on higher tiers.	Enterprise advertisers centralizing Amazon/Instacart/Walmart PPC with Machine Learning-driven bidding and budgeting.
Helium 10 (Adtomic)	Included in Helium 10 plans from ~$229/month + % of Ad Spend) *Ad Spend Based	Plan-based access	Standard support plus community resources & tutorials.	Sellers already using Helium 10 who want unified analytics + PPC automation in one suite.
Quartile	Custom pricing; commonly $500–$1,000+/month + % of Ad Spend *Ad Spend Based	Demo only	Onboarding plus dedicated account manager.	Larger brands managing many SKUs/markets needing Machine Learning-guided budget reallocation and scaling.
EVA AI	Starting price is from ~$97/month; no percentage fee disclosed *Subscription Based	Yes — 14 days	Email support; optional success manager on premium tiers.	Retail brands seeking an all-in-one platform for ads optimization, pricing, and inventory with Machine Learning.
BidX	Starting price is ~$199/mont + % of Ad Spend *Ad Spend Based	Yes — 14 days	Email & chat; guided onboarding and rules templates.	Small–mid-sized sellers who want automation with clear manual rule control; uses Machine Learning for suggestions.
Teikametrics	Starting price is ~$250/month + % of Ads Spend *Ad Spend Based	Yes — 30 days	Email & chat; dedicated support for larger accounts.	Brands advertising across Amazon + Walmart who want cross-platform optimization guided by Machine Learning.

1. Astra by Sellrbox

Full-Workflow AI Automation That Scales Profit, Not Just Bids

While most “AI” tools automate bids, Astra rewrites the entire playbook.

Built by the team behind Sellrbox, Astra automates the entire Amazon PPC workflow: keyword research, campaign creation, bid optimization, negative targeting, day-parting, etc; all guided by machine learning.

Why It Leads the List

• Three AI Optimization Modes: Profit, Sales, and Visibility algorithms adapt to your goals.

• Adaptive Learning: The more data (spend, clicks, conversions, etc) you feed Astra, the smarter it gets.

• Flexible Control: Manual override AI algorithms at any time.

• White-Glove Support: Unlimited strategy calls and audits with Amazon ad experts.

“We used Astra to grow our brands from $15 million to $35 million in six months.”

30 Day Free Trial: Start 30 Day Free Trial

Pricing: Free for 30 Days → flat fee + % of ad revenue. Transparent and performance-based.

2. Perpetua

Perpetua uses machine learning to manage bidding and budget allocation across Amazon, Instacart, and Walmart.
Its AI engine automatically adjusts keyword bids based on conversion likelihood and spend velocity.

• Best for enterprise advertisers who want to centralize PPC optimization across channels.

• Pricing: From $250/month with custom pricing tiers. No free trial.

3. Helium 10 (Adtomic)

Adtomic is Helium 10’s AI-enhanced advertising module, integrating directly with H10’s keyword and analytics suite.
It blends rule-based logic with AI insights for bid adjustments, keyword additions, and budget automation.

• Best for sellers already using the Helium 10 ecosystem who want a unified toolset.

• Pricing: Included in Helium 10 plans starting at $229/month, free trial available.

4. Quartile

Quartile leverages AI to predict the most profitable bid and budget combinations using historical and live campaign data.
Its algorithm continuously reallocates ad spend toward converting keywords and products.

• Best for larger brands managing multiple SKUs and marketplaces.

• Pricing: Custom pricing based on monthly ad spend (typically $500–$1,000/month). Free demo available.

5. EVA AI

Eva AI connects ad optimization with AI-driven pricing and inventory management.
Its deep-learning system analyzes thousands of signals to dynamically adjust bids, budgets, and product pricing to maximize profitability.

• Best for retail brands seeking a unified AI brain for ads + pricing.

• Pricing: From $97/month, with a 14-day free trial.

6. BidX

BidX offers AI-assisted bid management and campaign automation with smart rule suggestions.
While lighter than full AI platforms, it provides intuitive dashboards and predictive insights for small to mid-sized sellers.

• Best for sellers wanting affordable automation and visual clarity.

• Pricing: From $199/month, free trial available.

7. Teikametrics

Teikametrics’ Flywheel 2.0 platform uses machine learning to optimize Amazon and Walmart advertising.
Its AI models analyze conversion trends, keyword competitiveness, and market shifts to dynamically adjust bids and budgets for profitability.

• Best for brands selling across multiple channels seeking cross-platform AI optimization.

• Pricing: From $250/month, free trial available.

How to Choose the Right AI Amazon PPC Software

When comparing AI PPC tools, focus on:

1. True machine learning: not just static automation.

2. Scope: does it handle full workflow or only bids?

3. Transparency: can you see why AI made each decision?

4. Scalability: does performance improve as you grow?

5. Human support: can you get expert help when you need it?

Astra is the only platform that checks all five boxes, combining full AI automation with unlimited human guidance.

Still not sure which one is the best for your specific business goals?

Sign up for a free Strategy Session by Astra’s Expert Amazon PPC Team

Bottom Line

AI isn’t optional anymore, but not every “AI” tool delivers real intelligence.

If you want smarter ads, faster growth, and more profit, start with the only platform that automates everything and backs it with human expertise.

Related Reads

• 10 Best Amazon PPC Tools in 2025 (Comprehensive List)